Treatment of endometriosis with the antiprogesterone mifepristone

by endosolu

I have posted this and other ‘hormone’ related studies mainly to highlight the correlation I believe between a healthy hormonal system and a healthy women.

It seems fairly obvious that hormones have a role to play in endometriosis.

Can I suggest you do you own research on how hormones are made in the body and what nutrients are required for this to happen successfully… my guess is you are lacking substantially (don’t shoot the messenger 🙂

My thoughts are well discussed in the graphic below… we sell the only tre-en-en grain concentrate that I know of and its part of the endometriosis program we have been using successfully for many years.

Energy & Hormones Start with Nutritional Assurance at the Cellular level


OBJECTIVE: To evaluate the safety and efficacy of an antiprogesterone (mifepristone, RU486; Roussel-Uclaf, Romaineville, France) on endometriosis.

DESIGN: An open, prospective clinical trial.

SETTING: The clinical practice of an academic faculty.

PATIENTS: Nine women with endometriosis were studied.

INTERVENTIONS: RU486 (50 mg/d) was administered for 6 months.

MAIN OUTCOME MEASURES: Daily symptom inventories and urinary steroid metabolites were assessed before, during, and after treatment. Blood for hormone analysis was obtained weekly for 4 weeks and monthly thereafter. The extent of endometriosis, bone mineral density, circadian rhythm of cortisol, and LH pulsatility were determined before and after treatment. Safety laboratory measurements were made before and at 1, 2, and 6 months of treatment.

RESULTS: Pelvic pain and uterine cramping improved in all patients. Endometriosis regressed by 55%. All patients exhibited endocrine features of anovulatory amenorrhea without hypoestrogenism. A rise in serum LH and T levels was observed during the first month of treatment and one patient developed an elevation of liver transaminases during the last month of treatment. All other measurements were unchanged.

CONCLUSION: RU486 appears to be effective in improving the symptoms and causing regression of endometriosis in the absence of significant side effects.

Kettel, L. M., et al. “Treatment of endometriosis with the antiprogesterone mifepristone (RU486).” Fertility and sterility 65.1 (1996): 23-28.

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